Paraoxonase 2 Cys311Ser polymorphism and its association with the systolic blood pressure values in asymptomatic dyslipidemic individuals: a pilot study
Author:
Novotny Dalibor,Karasek David,Vaverkova Helena,Bartkova Margita,Kubickova Veronika
Abstract
AbstractThe study aimed to evaluate the relationship of paraoxonase 2 (Two hundred and sixty-four individuals were included in the study. The laboratory parameters were assessed by routine kit methods, while methods based on polymerase chain reaction were used for311 SS homozygous individuals had significantly lower systolic blood pressure values (SBP, p<0.01), C-reactive protein, and apolipoprotein A1 levels (p<0.05), as compared with C allele carriers. The analysis revealed no differences in the levels of endothelial/hemostatic markers, except for the increased adhesion molecule [soluble vascular cell adhesion molecule 1 (sVCAM-1)] concentrations in 311S/E2 carriers (p<0.05).The presence of the
Publisher
Walter de Gruyter GmbH
Subject
Biochemistry, medical,Medical Laboratory Technology,Clinical Biochemistry
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