Falsely decreased Abbott Alinity-c gamma-glutamyl transferase-2 result from paraprotein and heparin interference: case report and subsequent laboratory experiments
Author:
Affiliation:
1. Alfred Pathology Service , 5392 Alfred Health , Melbourne , VIC , Australia
2. Monash University , Melbourne , VIC , Australia
3. Department of Pathology , 3234 Northern Hospital Epping , Epping , VIC , Australia
Publisher
Walter de Gruyter GmbH
Link
https://www.degruyter.com/document/doi/10.1515/cclm-2024-0015/pdf
Reference9 articles.
1. Alberti, MO, Drake, TA, Song, L. The pH of chemistry assays plays an important role in monoclonal immunoglobulin interferences. Pract Lab Med 2015;3:8–16. https://doi.org/10.1016/j.plabm.2015.09.001.
2. Dimeski, G, Carter, A. Rare IgM interference with Roche/Hitachi Modular glucose and gamma-glutamyltransferase methods in heparin samples. Clin Chem 2005;51:2202. https://doi.org/10.1373/clinchem.2005.053561.
3. Graham, L, Dinesh, T, Syme, NR. Prevalence of paraprotein interference in three clinical chemistry analytes in a routine biochemistry laboratory. Ann Clin Biochem 2021;58:667–8. https://doi.org/10.1177/00045632211013862.
4. Australian medicines handbook online [Internet]. Protamine [updated Jul 2023]. Australia: Australian Medicines HandbookPty Ltd; 2023. https://amhonline.amh.net.au.acs.hcn.com.au/chapters/blood-electrolytes/drugs-reversing-anticoagulation/protamine [Accessed 12 Sep 2023].
5. Mylon, E, Winternitz, MC, de Suto-Nagy, GJ. The determination of fibrinogen with protamine. J Biol Chem 1942;143:21–7. https://doi.org/10.1016/S0021-9258(18)72654-9.
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