Diagnostic algorithms for non-ST-segment elevation myocardial infarction: open issues-Reference-Cited by-同舟云学术

Diagnostic algorithms for non-ST-segment elevation myocardial infarction: open issues

Published:2021-07-06 Issue:11 Volume:59 Page:1761-1771
ISSN:1434-6621
Container-title:Clinical Chemistry and Laboratory Medicine (CCLM)
language:en
Short-container-title:

Author:

Clerico Aldo¹,Aimo Alberto¹,Zaninotto Martina²,Plebani Mario²^ORCID

Affiliation:

1. Scuola Superiore Sant’Anna e Fondazione CNR – Regione Toscana G. Monasterio , Pisa , Italy

2. Dipartimento di Medicina di Laboratorio , Azienda Ospedaliera Universitaria di Padova, e Dipartimento di Medicina – Università di Padova , Padova , Italy

Abstract

Abstract The use of serial measurement of cardiac troponin (cTn) is recommended by international guidelines for the diagnosis of myocardial infarction (MI) since 2000. This article focuses on factors influencing temporal changes in high-sensitive cTn (hs)-cTn and the impact of these factors on the diagnosis of non-ST-segment elevation MI (NSTEMI). The recommendations proposed by three different international guidelines published in 2020–2021 for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation (NSTE) show some discrepancies. In particular, there is no agreement among these guidelines about cut-off or absolute change values to be used for the rule-in, especially regarding the use of sex-specific cut-off values. Furthermore, there are no sufficient evidences on the diagnostic accuracy and cost effectiveness related to cut-off values suggested for algorithms to be used by some hs-cTnI methods.

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry, medical,Clinical Biochemistry,General Medicine

Link

https://www.degruyter.com/document/doi/10.1515/cclm-2021-0550/pdf

Reference87 articles.

1. Alpert, JS, Thygesen, K, Antman, E, Bassand, JP. Myocardial infarction redefined: a consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol 2000;36:959–69. https://doi.org/10.1016/s0735-1097(00)00804-4.

2. Clerico, A, Zaninotto, M, Ripoli, M, Masotti, S, Prontera, C, Passino, C, et al.. The 99th percentile of reference population for cTnI and cTnT assay: methodology, pathophysiology, and clinical implications. Clin Chem Lab Med 2017;55:1634–51. https://doi.org/10.1515/cclm-2016-0933.

3. Clerico, A, Zaninotto, M, Padoan, A, Masotti, S, Musetti, V, Prontera, C, et al.. Evaluation of analytical performance of immunoassay methods for cardiac troponin I and T: from theory to practice. Adv Clin Chem 2019;93:239–62. https://doi.org/10.1016/bs.acc.2019.07.005.

4. Wu, AHB, Christenson, RH, Greene, DN, Jaffe, AS, Kavsak, PA, Ordonez-Lianos, J, et al.. Clinical laboratory practice recommendations for the use of cardiac troponin in acute coronary syndrome: expert opinion from the Academy of the American Association for Clinical Chemistry and the Task Force on Clinical Applications of Cardiac Bio-Markers of the International Federation of Clinical Chemistry and Laboratory Medicine. Clin Chem 2018;64:645–55. https://doi.org/10.1373/clinchem.2017.277186.

5. Thygesen, K, Alpert, JS, Jaffe, AS, Chaitman, BR, Bax, JJ, Morrow, DA, et al.. Fourth universal definition of myocardial infarction. J Am Coll Cardiol 2018;72:2231–64. https://doi.org/10.1016/j.jacc.2018.08.1038.

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