A new method for early cancer detection based on platelet transcriptomics will have low positive predictive value
Author:
Affiliation:
1. Department of Pathology and Laboratory Medicine , Mount Sinai Hospital, University Health Network and University of Toronto , Toronto , ON , Canada
Publisher
Walter de Gruyter GmbH
Subject
Biochemistry (medical),Clinical Biochemistry,General Medicine
Link
https://www.degruyter.com/document/doi/10.1515/cclm-2022-1025/pdf
Reference9 articles.
1. In ’t Veld, SGJG, Arkani, M, Post, E, Antunes-Ferreira, M, D’Ambrosi, S, Vessies, DCL, et al.. Detection and localization of early- and late-stage cancers using platelet RNA. Cancer Cell 2022;40:999–1009.e6. https://doi.org/10.1016/j.ccell.2022.08.006.
2. Fernandez-Uriarte, A, Pons-Belda, OD, Diamandis, EP. Cancer screening companies are rapidly proliferating: are they ready for business? Cancer Epidemiol Biomarkers Prev 2022;31:1146–50. https://doi.org/10.1158/1055-9965.epi-22-0102.
3. Anonymous. NCI to study cancer blood tests. Science 2022;377:8.
4. Wilson, JMG, Jungner, G, World Health Organization. Principles and practice of screening for disease; 1968. Available from: https://apps.who.int/iris/handle/10665/37650.
5. Fiala, C, Diamandis, EP. A multi-cancer detection test: focus on the positive predictive value. Ann Oncol 2020;31:1267–8. https://doi.org/10.1016/j.annonc.2020.05.028.
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