Influence of delayed separation of plasma from whole blood and centrifugation protocol on Zn plasma concentration

Author:

Leger Mandy1,Despinasse Quentin1,Faure Patrice12,Arnaud Josiane1,Ravelet Corinne34,Chovelon Benoit134

Affiliation:

1. Institute of Biology and Pathology , University Hospital of Grenoble and Alps , Grenoble , France

2. University Grenoble Alpes , Laboratory of Hypoxy Physiopathology Study Inserm U1042 , La Tronche , France

3. University Grenoble Alpes , DPM UMR 5063 , Grenoble , France

4. CNRS , DPM UMR 5063 , Grenoble , France

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry (medical),Clinical Biochemistry,General Medicine

Reference10 articles.

1. Killilea, DW, Rohner, F, Ghosh, S, Otoo, GE, Smith, L, Siekmann, JH, et al. Identification of a hemolysis threshold that increases plasma and serum zinc concentration. J Nutr 2017 Jun;147:1218–25. https://doi.org/10.3945/jn.116.247171.

2. https://static1.squarespace.com/static/56424f6ce4b0552eb7fdc4e8/t/5748af1637013bafc39 ab0a1/1464381209938/IZiNCGtechdocFNB2004.pdf published in International Zinc Nutrition Consultative Group. Assessment of the risk of zinc deficiency in populations and options for its control. Food Nutr Bull 2004;25:S94–204.

3. English, JL, Hambidge, KM. Plasma and serum zinc concentrations: effect of time between collection and separation. Clin Chim Acta 1988;175:211–5. https://doi.org/10.1016/0009-8981(88)90097-6.

4. World Health Organization. Use of anticoagulants in diagnostic laboratory investigations, WHO/DIL/LAB/99.1 rev.2. Geneva: WHO; 2002.

5. Chovelon, B, Arnaud, J. Influence of delayed separation of plasma from whole blood on Cu, I, Mn, Se, and Zn plasma concentrations. Clin Chem Lab Med 2018;56:e69–71. https://doi.org/10.1515/cclm-2017-0358.

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