An Improved Preparation of 11,19-Oxidopregn-4-ene-3,20-dione and 6,19-Oxidopregn-4-ene-3,11,20-trione-Reference-Cited by-同舟云学术

An Improved Preparation of 11,19-Oxidopregn-4-ene-3,20-dione and 6,19-Oxidopregn-4-ene-3,11,20-trione

Published:1990-05-01 Issue:5 Volume:45 Page:711-716
ISSN:1865-7117
Container-title:Zeitschrift für Naturforschung B
language:en
Short-container-title:

Author:

Brachet-Cota Adriana L.¹,Burton Gerardo¹

Affiliation:

1. Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, (1428) Buenos Aires, Argentina

Abstract

A synthesis of 11,19-oxidopregn-4-ene-3,20-dione and 6,19-oxidopregn-4-ene-3,11,20-trione is described starting from pregn-4-ene-3,11,20-trione and via the common intermediate 3β,20β-diacetyloxy-5α-bromo-6,19-oxidopregnan-11-one, in 30 and 32% yield, respectively.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/znb-1990-0521/pdf

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