Steroids from Aquatic Organisms, XIX. New Sterols from the Antarctic Sponge Artemisina apollinis

Abstract

Abstract The steroidal composition of the sponge Artemisina apollinis from the Antarctic Ocean was studied by GC-MS and 'H NMR. The sponge contains twenty-eight C 25—C30 derivatives having four different types of nucleus: 3/3-hydroxy-5aH-, 3-keto-5aH-derivatives, 3/3-hydroxy-zl5-and 3/?-hydroxy-zl7-derivatives. Compounds with the first two nucleus are the most abundant, with similar side chain patterns and identical GC profiles. The 3-keto-5aH-derivatives constitute a new group of natural products.