Synthese biologisch aktiver Peptide mittels eines neuen Syntheseautomaten / Synthesis of Biological Active Peptides by the Aid of a New Peptide Synthesizer

Author:

Voelter W.1,Zech K.1,Grubhofer N.2

Affiliation:

1. Chemisches Institut der Universität Tübingen und

2. Serva-Technik, Heidelberg

Abstract

A new automatic peptide synthesizer is described. Most of the different single parts of apparates like the programmer, timer, “Multiport-Ventil,” magnetic valves or vessels are all commercially available and may be fixed together with a relatively small amount of costs. The efficiency of the new apparatus is tested by the automatic synthesis of biologically active peptide sequences like H-Asp(OH)-Ala-Phe-Ile-Gly-Leu-Met-NH2, H-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2 and Pyr-Tyr-Arg-Trp-NH2.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. References;Reactivity and Structure: Concepts in Organic Chemistry;1978

2. Hypothalamus-Regulationshormone;Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products;1977

3. A programmable control system for the automatic synthesis of polypeptides;Journal of Physics E: Scientific Instruments;1975-08

4. ChemInform Abstract: SYNTHESE BIOLOGISCH AKTIVER PEPTIDE MITTELS EINES NEUEN SYNTHESEAUTOMATEN;Chemischer Informationsdienst;1974-03-26

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