Preliminary results of Highly Injectable Bi-Phasic Bone Substitute (CERAMENT) in the treatment of benign bone tumors and tumor-like lesions

Author:

Kotrych Daniel1,Korecki Szymon1,Ziętek Paweł2,Kruk Bartosz1,Kruk Agnieszka3,Wechmann Michał1,Kamiński Adam4,Kotrych Katarzyna1,Bohatyrewicz Andrzej1

Affiliation:

1. Department of Orthopaedics, Traumatology and Orthopaedic Oncology , Pomeranian Medical University in Szczecin , Poland

2. Pomeranian Medical University , Szczecin , Poland

3. Department of Pediatrics, Pediatric Hematology and Oncology , Pomeranian Medical University in Szczecin , Poland

4. Department of Pediatric Orthopaedics and Traumatology , Pomeranian Medical University in Szczecin , Poland

Abstract

Abstract Background: CERAMENT™|BONE VOID FILLER is an injectable and moldable ceramic bone substitute material intended for bone voids. The material consists of hydroxyapatite and calcium sulfate hemihydrate. The aim of this study is to present the first long-term results following open curettage of benign bone tumors and tumor-like lesions and void filling with this novel injectable and synthetic bone graft. Methods: Thirty three patients were enrolled into the study between June 2013 and October 2014 .Totally, we treated 24 women and 9 men with a median age of 47 years (range: 22-74). All patients suffered from primary musculoskeletal system disorders (enchondroma 63,6%, giant cell tumor 18%, aneurysmal bone cyst 9%, fibrous dysplasia 9%, Gaucher disease 3%). We performed curettage of pathological lesions, then the bone substitute was administered by means of needle to the void. Results: The average follow-up was 13 months (range: 2-13 months, median 10 months). No metastasis or recurrence had been detected. We received significant clinical improvement relating to VAS, MSTS, and oncological results. Conclusions: The results of our study report that CERAMENT can be successfully used as a bone substitute in patients with various bone diseases, as well as benign bone tumors. CERAMENT can provide an effective and long-term solution for reconstructive procedures following curettage of bone tumors and tumor like lesions.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Reference12 articles.

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