Affiliation:
1. High and New Technology Research Center of Henan Academy of Sciences, Zhengzhou 450002, P. R. China
2. International Education College of Henan University, Kaifeng 475001, P. R. China
Abstract
AbstractN-Hydroxyethyl-substituted 1,2,3,4-tetrahydroquinolines were synthesized by the reaction of 2-(phenylamino)ethanol with unsaturated ketone catalyzed by acidic ionic liquid N-methyl-2-pyrrolidonium dihydrogen phosphate [NMPH]H2PO4, obviating the need for toxic and expensive catalysts. The acidic ionic liquid not only showed superior performance over H3PO4 but also was stable and could be reused at least five times with a slight loss of activity. It provided a straightforward and efficient protocol for the synthesis of 1,2,3,4-tetrahydroquinoline derivatives.
Subject
Health, Toxicology and Mutagenesis,Industrial and Manufacturing Engineering,Fuel Technology,Renewable Energy, Sustainability and the Environment,General Chemical Engineering,Environmental Chemistry