Cardiovascular disease, mortality and exposure to particulate matter (PM): a systematic review and meta-analysis

Author:

Mohammadi Mohammad Javad12,Fouladi Dehaghi Behzad3,Mansourimoghadam Sara4,Sharhani Asaad5,Amini Payam6,Ghanbari Saeed7

Affiliation:

1. Department of Environmental Health Engineering, School of Public Health and Environmental Technologies Research Center , Ahvaz Jundishapur University of Medical Sciences , Ahvaz , Iran

2. Air Pollution and Respiratory Diseases Research Center , Ahvaz Jundishapur University of Medical Sciences , Ahvaz , Iran

3. Department of Occupational Health, School of Health, Environmental Technology Research Center , Ahvaz Jundishapur University of Medical Sciences , Ahvaz , Iran

4. Department of Environment , Ahvaz Branch, Islamic Azad University , Ahvaz , Iran

5. Department of Biostatistics and Epidemiology, School of Health , Iran University of Medical Sciences , Tehran , Iran

6. Department of Biostatistics , School of Public Health , Iran University of Medical Sciences , Tehran , Iran

7. Department of Biostatistics and Epidemiology, School of Health , Ahvaz Jundishapur University of Medical Sciences , Ahvaz , Iran

Abstract

Abstract One of the main factors that causes health effects in humans such as hospital admissions for cardiovascular disease (HACVD), respiratory disease (RD), lung function, cardiovascular mortality (MCVD), lung cancer, and increased mortality is air pollution especially particulate matter (PM). This a systematic review and meta-analysis aims to investigate the effects of particulate matter on the occurrence of cardiovascular disease and mortality. A systematic review and meta-analysis of the literature was done from 2011 to 2021 based on various databases. Based on the result of this study, subgroup analysis based on temperature conditions showed a different estimation in cold cities (6.24, UR (4.36–8.12)), moderate cities (4.86, UR (3.57–6.15)) and warm cities (8.96, UR (7.06–10.86)). Test of group differences showed a significant difference (Q=12.22, p-value<0.001). There was publication bias among the studies (the Egger’s test; (Z=14.18, p<0.001)). According result study pooled estimation of AP% for MCVD from the random-effect meta-analysis based on DerSimonian-Laird model, overall is 5.04, UR (3.65–6.43) (Figure 4). Subgroup analysis based on temperature conditions showed the estimation in cold cities (5.47, UR (3.97–6.97)) and moderate cities (4.65, UR (0.54–8.77)). Test of group differences showed a non-significant difference (Q=0.13, p-value=0.71). There was no publication bias among the studies (the Egger’s test; (Z=0.82, p=0.376)). Exposed to air pollutants and particulate matter can be increase the risk of cardiovascular disease, respiratory disease, and cardiovascular mortality.

Funder

Ahvaz Jundishapur University of Medical Sciences

Publisher

Walter de Gruyter GmbH

Subject

Public Health, Environmental and Occupational Health,Pollution,Health (social science)

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