Sensory testing might not be perfect – but it is the best biomarker for pain phenotypes we have right now

Author:

Vollert Jan1234

Affiliation:

1. Pain Research, Department of Surgery and Cancer , Imperial College London , London , UK

2. Division of Neurological Pain Research and Therapy, Department of Neurology , University Hospital of Schleswig-Holstein , Campus Kiel , Kiel , Germany

3. Department of Anaesthesiology, Intensive Care and Pain Medicine , University Hospital Muenster , Muenster , Germany

4. Neurophysiology , Mannheim Center of Translational Neuroscience (MCTN), Medical Faculty Mannheim, Heidelberg University , Heidelberg , Germany

Abstract

Abstract Currently available treatments for neuropathic pain fail in roughly half of the patients – and it is impossible to predict which treatments will help patients. Stratification of neuropathic pain patients is needed, and sensory profiling has so far been the most promising approach: it has been shown to be responsive to treatment, linked to potential mechanisms, and, most importantly, predictive of treatment success. Despite a number of limitations, it is the currently most promising stratification tool and should be refined rather than disregarded.

Publisher

Walter de Gruyter GmbH

Subject

Anesthesiology and Pain Medicine,Neurology (clinical)

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