A Facile and Catalyst-free Synthesis of Hexahydroacridine-1,8(2H,5H )-dione and Octahydroacridin-10(1H )-yl)thiourea Derivatives: Inter- and Intramolecular Aza-Michael addition-Reference-Cited by-同舟云学术

A Facile and Catalyst-free Synthesis of Hexahydroacridine-1,8(2H,5H )-dione and Octahydroacridin-10(1H )-yl)thiourea Derivatives: Inter- and Intramolecular Aza-Michael addition

Published:2020-03-10 Issue:1 Volume:26 Page:26-32
ISSN:2191-0197
Container-title:Heterocyclic Communications
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Author:

Pesyan Nader Noroozi¹,Akhteh Narmin¹,Batmani Hana¹,Anıl Barış²,Şahin Ertan²

Affiliation:

1. Department of Organic Chemistry, Faculty of Chemistry, Urmia University, 57159, Urmia, IRAN

2. Department of Chemistry, Faculty of Science, Atatürk University, 25240Erzurum, Turkey

Abstract

AbstractAn easy and convenient technique for the one-pot synthesis of novel compounds of hexahydroacridine-1,8(2H,5H)-dione and octahydroacridin-10(1H)-yl) thiourea derivatives has been developed by the reaction of the octahydro-1H-xanthenes with hydroxylamine hydrochloride and thiosemicarbazide in ethylene glycol, which is a green solvent, under mild reaction conditions. IR, 1H NMR, 13C NMR spectrometry, and X-ray diffraction analysis were used to identify the structures of these compounds.

Publisher

Walter de Gruyter GmbH

Subject

Organic Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/hc-2020-0005/pdf

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