A19-saponin–modified polymethyl methacrylate base denture composites: antimicrobial, mechanical and water absorption potentials
Author:
Azeez Taofik Oladimeji1ORCID, Iroh Grace Onyinyechi2, Odetunde Daniel Segun2, Egbuonu Amaka Tessy2, Agbasi Patrick Ugochukwu3
Affiliation:
1. Department of Biomedical Engineering, School of Engineering and Engineering Technology , Federal University of Technology , Owerri , Nigeria 2. Department of Biomedical Engineering , Federal University of Technology , Owerri , Nigeria 3. Department of Prosthesis and Othosis , Federal University of Technology , Owerri , Nigeria
Abstract
Abstract
The increased growth of Candida albicans (C. albicans) with allergy reaction of MMA remains an issue of concern among denture wearers. C. albicans growth inhibition, mechanical and water absorption potentials of extracted A19-saponin–commingled PMMA denture base composites were investigated. Soxhlet extraction technique for defatting of Dialium guineense (D. guineense) stem powder was used with ethanol to extract A19-saponin. Fungicidal inhibition concentration of A19-saponin extract of D. guineense was determined. PMMA denture base was prepared with incorporation of A19-saponin at different concentrations of obtained 23.2 % yield. The mechanical and water absorption properties were determined. The minimum and maximum fungicidal inhibition concentrations and susceptibility of 25 and 100 % for extracted A19-saponin were obtained, respectively. PMMA, MMA and extracted A19-saponin of ratio of 30 g: 5 ml: 5 ml denture was optimally fabricated. A19-saponin increased the impact strength and hardness by 352.94 and 11.54 % with reduced water absorption by 82.85 %. Thus, A19-saponin as an additive improved quality of denture.
Publisher
Walter de Gruyter GmbH
Subject
Mechanical Engineering,Mechanics of Materials,General Materials Science
Reference55 articles.
1. C. Haberland-Carrodeguas, M. A. Carl, F. B. Micheal, J. B. William, L. K. Susan, and S. Paula, “Prevalence of fluconazole-resistant strains of Candida albicans in otherwise healthy outpatients,” J. Oral Pathol. Med., vol. 31, no. 2, pp. 99–105, 2002, https://doi.org/10.1034/j.1600-0714.2002.310207.x. 2. P. Sandven, “Epidemiology of candidemia,” Rev. Iberoam. De. Micol., vol. 17, no. 3, pp. 73–81, 2000. 3. G. Alvydas, Z. Eglė, and Ž. Juozas, “Candida albicans importance to denture wearers,” Stomatologija, Baltic Dent. Maxillofacial J., vol. 17, pp. 54–66, 2015. 4. L. Gendreau and Z. G. Loewy, “Epidemiology and etiology of denture stomatitis,” J. Prosthodontics, vol. 20, no. 4, pp. 251–260, 2011, https://doi.org/10.1111/j.1532-849X.2011.00698.x. 5. T. S. Gonçalves, M. A. Morganti, L. C. Campos, S. M. D. Rizzatto, and L. M. Menezes, “Allergy to auto-polymerized acrylic resin in an orthodontic patient,” Am. J. Orthod. Dentofacial Orthop., vol. 129, no. 3, pp. 431–435, 2006, https://doi.org/10.1016/j.ajodo.2005.10.017.
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