An Antiviral Meliacarpin from Leaves of Melia azedarach L.-Reference-Cited by-同舟云学术

An Antiviral Meliacarpin from Leaves of Melia azedarach L.

Published:2003-04-01 Issue:3-4 Volume:58 Page:215-219
ISSN:1865-7125
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Alché Laura E.¹,Assad Ferek Guillermo¹,Meo Milena²,Coto Celia E.¹,Maier Marta S.²

Affiliation:

1. Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina

2. Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina

Abstract

Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 μᴍ and 20 μᴍ for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-2003-3-413/pdf

Cited by 39 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evaluation of Safety and Efficacy of Clevira Tablets Against Influenza Viruses: Randomized Open Label Clinical Study;American Journal of Biochemistry and Molecular Biology;2024-01-15

2. An efficient method for hairy root transformation and transgenic plant regeneration of Melia azedarach;Plant Cell, Tissue and Organ Culture (PCTOC);2023-12-07

3. Chemical Composition and Bioactivities of Melia azedarach (Meliaceae): A Comprehensive Review;Current Organic Chemistry;2023-12

4. In vivo evaluation of the antiretroviral activity of Melia azedarach against small ruminant lentiviruses in goat colostrum and milk;Brazilian Journal of Microbiology;2023-11-27

5. Classification of Medicinal Plants Showing Anti-Viral Activity, Classified by Family and Viral Infection Types;Reference Series in Phytochemistry;2023-11-01