Regioselective C-3 arylation of coumarins with arylhydrazines via radical oxidation by potassium permanganate-Reference-Cited by-同舟云学术

Regioselective C-3 arylation of coumarins with arylhydrazines via radical oxidation by potassium permanganate

Published:2016-08-30 Issue:11 Volume:71 Page:1115-1123
ISSN:1865-7117
Container-title:Zeitschrift für Naturforschung B
language:en
Short-container-title:

Author:

Yuan Jin-Wei¹,Li Wei-Jie¹,Yang Liang-Ru¹,Mao Pu¹,Xiao Yong-Mei¹

Affiliation:

1. School of Chemistry and Chemical Engineering, Henan University of Technology; Academician Workstation for Natural Medical Chemistry of Henan Province, Zhengzhou 450001, P.R. China

Abstract

Abstract An efficient protocol for oxidative C-3 arylation of coumarins with arylhydrazine has been developed using potassium permanganate as an oxidant. The arylated coumarins with different electronic properties were obtained in moderate to good yields. The developed protocol for direct C-3 arylation of coumarins could be extended to quinolinones.

Funder

National Natural Science Foundation of China

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

Link

https://www.degruyter.com/document/doi/10.1515/znb-2016-0109/pdf

Reference50 articles.

1. M. A. Musa, J. S. Cooperwood, M. Khan, F. Omar, Curr. Med. Chem. 2008, 15, 2664.

2. I. Kempen, D. Papapostolou, N. Thierry, L. Pochet, S. Counerotte, B. Masereel, J. M. Foidart, M. J. Reboud-Ravaux, A. Noel, B. Pirotte, Br. J. Cancer2003, 88, 1111.

3. C. Spino, M. Dodier, S. Sotheeswaran, Bioorg. Med. Chem. Lett. 1998, 8, 3475.