Radiation effects of nuclear physics rays on hepatoma cells-Reference-Cited by-同舟云学术

Radiation effects of nuclear physics rays on hepatoma cells

Published:2019-01-01 Issue:1 Volume:17 Page:167-176
ISSN:2391-5471
Container-title:Open Physics
language:en
Short-container-title:

Author:

Zhao Wenhui¹,Cong Lu²,Guerrero-Sánchez Yolanda³

Affiliation:

1. College of Science, Harbin Engineering University , Harbin , 150001 , China

2. College of Information and Communication Engineering, Harbin Engineering University , Harbin , 150001 , China

3. Departamento de Demartología, Estomatología y Medicna Física. Área de Medicina Bucal. Universidad de Murcia , Murcia , Spain

Abstract

Abstract The traditional method of cloning formation is used to study the radiation effect of nuclear physics rays on hepatoma cells, and the results obtained are not reliable. Therefore, a new method of studying the radiation effect of nuclear physics rays on hepatoma cells is proposed. PCC method is used to study the radiation effect of γ-rays on hepatoma cells. Radiation effects of X-rays on hepatoma cells were studied by radionuclide formation assay, neutral comet electrophoresis and γH2AX focal detection. The results showed that the survival curves of HepG2 hepatoma cells irradiated by γ-rays were well fitted by linear squares. There was a linear relationship between the survival rate and irradiation dose of HepG2 hepatoma cells irradiated by γ-rays. HepG2 hepatoma cells showed strong tolerance to X-ray irradiation, and the positive rate of γH2AX cells reached 100% in each dose group only 0.5 h after X-ray irradiation.

Publisher

Walter de Gruyter GmbH

Subject

General Physics and Astronomy

Link

https://www.degruyter.com/document/doi/10.1515/phys-2019-0017/pdf

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