Survival of node-negative breast cancer patients treated at the university medical centre Maribor in the period 2000–2009

Author:

Fokter Dovnik Nina1,Arko Darja2,Čas Sikošek Nina2,Takač Iztok23

Affiliation:

1. University Medical Centre Maribor , Department of Oncology , Ljubljanska 5, 2000 Maribor , Slovenia

2. University Medical Centre Maribor , University Clinical Department of Gynaecology and Perinatology , Ljubljanska 5, 2000 Maribor Slovenia

3. University of Maribor , Faculty of Medicine , Taborska 8, 2000 Maribor Slovenia

Abstract

Abstract Introduction Breast cancer is increasingly diagnosed in the early stages without regional nodal involvement. The aim of the present study was to determine the 5-year overall (OS) and breast cancer specific survival (BCSS) for patients with node-negative breast cancer treated at the University Medical Centre Maribor, and compare it with survival at the national level. Methods Medical records were searched for information on patients with lymph node-negative invasive breast cancer who received primary treatment at the University Medical Centre Maribor in the period 2000–2009. Information on all Slovenian node-negative breast cancer patients diagnosed in the same period was obtained from the Cancer Registry of Republic of Slovenia. Time trends in survival were assessed by comparing the periods 2000–2004 and 2005–2009. Results The 5-year OS and BCSS of patients treated in Maribor in the period 2000–2009 were 92.3% (95% CI, 90.5%– 94.1%) and 96.4% (95% CI, 95.2%–97.6%), respectively, and did not differ from the corresponding OS and BCSS for Slovenian patients. Although the improvement in OS for patients from Maribor diagnosed in the period 2005–2009 compared to 2000–2004 did not reach statistical significance (HR 0.73; 95% CI, 0.51–1.05; p=0.086), BCSS significantly improved over the same time periods (HR 0.53; 95% CI, 0.30–0.94; p=0.028). Conclusions Survival of node-negative breast cancer patients treated at the University Medical Centre Maribor is comparable to survival of corresponding patients at the national level. The rising number of long-term breast cancer survivors places additional importance on survivorship care.

Publisher

Walter de Gruyter GmbH

Subject

Public Health, Environmental and Occupational Health

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