Author:
Timmerman Annemoon M.,Snijder Roland A.,Lucas Peter,Lagerweij Martine C.,Radermacher Joris H.,Konings Maurits K.
Abstract
AbstractMulti-infusion therapy, in which multiple pumps are connected to one access point, is frequently used in patient treatments. This practice is known to cause dosing errors following setpoint changes in the drug concentrations that actually enter the patients. Within the Metrology for Drug Delivery Project, we analyzed and quantified the two main physical phenomena leading to these errors: the “push-out” effect and the system mechanical compliance. We compared the dosing errors of a three-pump system with two infusion sets, both with and without anti-reflux valves, using
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