The role of osteoprotegerin in the development, progression and management of abdominal aortic aneurysms-Reference-Cited by-同舟云学术

The role of osteoprotegerin in the development, progression and management of abdominal aortic aneurysms

Published:2020-05-26 Issue:1 Volume:15 Page:457-463
ISSN:2391-5463
Container-title:Open Medicine
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Author:

Migacz Maciej¹,Janoska-Gawrońska Agata¹,Holecki Michał¹,Chudek Jerzy²

Affiliation:

1. Department and Clinic of Internal, Autoimmune and Metabolic Diseases, Faculty of Medicine, Medical University of Silesia in Katowice, Poland

2. Department and Clinic of Internal Medicine and Cancer Chemotherapy, Faculty of Medicine, Medical University of Silesia in Katowice, Poland

Abstract

AbstractOsteoprotegerin (OPG) appears to be a very promising marker both in the diagnosis of abdominal aortic aneurysms (AAAs) and as a potential target in its treatment. This article presents an overview of the current literature that discusses the role of OPG in the pathogenesis of atherosclerosis and its potential value as a prognostic factor in AAA. Pharmacological modulation of OPG expression has been considered. In conclusion, it seems that further research designed to assess the relationship between OPG and AAA is needed as this may contribute to improved AAA monitoring and more effective treatment of patients with AAA.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Link

https://www.degruyter.com/document/doi/10.1515/med-2020-0046/pdf

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