Directed differentiation into insulin-producing cells using microRNA manipulation
Author:
Affiliation:
1. Diabetes and Islet biology Group, NHMRC Clinical Trials Centre, Faculty of Medicine and Health, The University of Sydney, Level 6, Medical Foundation Building, 92-94 Parramatta Road, Camperdown, NSW 2050, Australia
Abstract
Publisher
Walter de Gruyter GmbH
Subject
General Medicine
Link
https://www.degruyter.com/document/doi/10.1515/med-2020-0170/pdf
Reference34 articles.
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2. Expression of islet-specific microRNAs during human pancreatic development;Gene Expression Patterns,2009
3. The small RNA miR-375 – a pancreatic islet abundant miRNA with multiple roles in endocrine beta cell function;Mol Cell Endocrinol,2017
4. Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells;Nat Biotechnol,2014
5. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells;Nature,2008
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1. Differentially expressed microRNAs during the differentiation of muscle-derived stem cells into insulin-producing cells, a promoting role of microRNA-708-5p/STK4 axis;PLOS ONE;2022-04-08
2. Machine learning workflows identify a microRNA signature of insulin transcription in human tissues;iScience;2021-04
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