Bioactive Compounds of the Volatile Oil of Dracocephalum kotschyi-Reference-Cited by-同舟云学术

Bioactive Compounds of the Volatile Oil of Dracocephalum kotschyi

Published:2007-12-01 Issue:11-12 Volume:62 Page:793-796
ISSN:1865-7125
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Saeidnia Soodabeh¹,Gohari Ahmad Reza¹,Hadjiakhoondi Abbas²,Shafiee Abbas³

Affiliation:

1. Medicinal Plants Research Center, Faculty of Pharmacy, Medical Sciences/University of Tehran, P. O. Box 14155-6451, Tehran, Iran

2. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

3. Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Trypanocidal activity was found in the volatile oil of dried Dracocephalum kotschyi. GCMS analysis determined that the major constituents of the oil were geranial (35.8%), C10H14O (26.6%), limonene (15.8%) and 1,1-dimethoxy decane (14.5%). In order to isolate the unknown biologically active monoterpene, fractionation of the volatile oil was carried out by silica gel column chromatography. The structure of the oxygenated compound was confirmed to be limonene-10-al (C10H14O) by analysis of physical and spectroscopic data (1H NMR, 13C NMR, HMBC and HMQC).

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-2007-11-1203/pdf

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