The AGO proteins: an overview-Reference-Cited by-同舟云学术

The AGO proteins: an overview

Published:2018-02-15 Issue:6 Volume:399 Page:525-547
ISSN:1437-4315
Container-title:Biological Chemistry
language:en
Short-container-title:

Author:

Niaz Saife¹

Affiliation:

1. Department of Biotechnology , University of Kashmir , Srinagar 190006, Jammu and Kashmir , India

Abstract

Abstract Small RNAs govern almost every biological process in eukaryotes associating with the Argonaute (AGO) proteins to form the RNA-induced silencing complex (mRISC). AGO proteins constitute the core of RISCs with different members having variety of protein-binding partners and biochemical properties. This review focuses on the AGO subfamily of the AGOs that are ubiquitously expressed and are associated with small RNAs. The structure, function and role of the AGO proteins in the cell is discussed in detail.

Publisher

Walter de Gruyter GmbH

Subject

Clinical Biochemistry,Molecular Biology,Biochemistry

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