Abstract
Abstract
A diversity-oriented synthesis of amide-containing thieno[2,3-d]pyrimidin-4(3H)-ones is reported. All compounds were tested for their influence on melanin synthesis in murine B16 cells. The azepine fragment in thieno[2,3-d]pyrimidin-4(3H)-one skeleton significantly increases the melanin content.
Reference40 articles.
1. Safety and therapeutic effectiveness of 8-methoxypsoralen, 4,5′,8-trimethylpsoralen, and psoralen in vitiligo;National Cancer Institute Monograph,1984
2. Synthesis and bioactivity of novel isoxazole chalcone derivatives on tyrosinase and melanin synthesis in murine B16 cells for the treatment of vitiligo;Bioorg. Med. Chem.,2016
3. Recent report on thieno[2,3-d]pyrimidines. Their preparation including microwave and their utilities in fused heterocycles synthesis;J. Heterocycl. Chem.,2013
4. Synthesis and biological evaluation of furocoumarin derivatives on melanin synthesis in murine B16 cells for the treatment of vitiligo;Bioorg. Med. Chem.,2016
5. Therapeutic interventions for vitiligo;J. Am. Acad. Dermatol.,2008
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