Chemoselective silver-catalyzed nitrene insertion reactions

Abstract

AbstractA review of recent developments in silver(I)-catalyzed nitrene insertions into olefin and C–H bonds is presented, with a particular emphasis on reactions where the chemoselectivity can be tuned to promote either aziridination or C–H amination. The scope and synthetic utility of various silver catalysts are described, as well as preliminary investigations into the mechanisms of silver-catalyzed aminations.