3,7-Isoquinoline quinones from the ascidian tunicate Ascidia virginea-Reference-Cited by-同舟云学术

3,7-Isoquinoline quinones from the ascidian tunicate Ascidia virginea

Published:2017-04-28 Issue:7-8 Volume:72 Page:259-264
ISSN:1865-7125
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Possner Sven T.¹²,Schroeder Frank C.²,Rapp Hans Tore³,Sinnwell Volker¹,Franke Stefan¹,Francke Wittko⁴

Affiliation:

1. Institute of Organic Chemistry , University of Hamburg , Martin-Luther-King-Platz 6 , D-20146 Hamburg , Germany

2. Boyce Thompson Institute and Department of Chemistry and Chemical Biology , Cornell University , Ithaca , NY 14853-1301 , USA

3. Department of Biology and K.G. Jebsen Centre for Deep-Sea Research , University of Bergen , PO Box 7800 , N-5020 Bergen , Norway

4. Institute of Organic Chemistry , University of Hamburg , Martin-Luther-King-Platz 6 , D-20146 Hamburg , Germany , Tel.: (+49) 40 42838-2866

Abstract

Abstract A new isoquinoline quinone system and its iodinated derivatives were isolated from the ascidian tunicate Ascidia virginea Müller 1776 (Phlebobranchia: Ascidiidae). Structures were elucidated by spectroscopic methods and derivatization reactions. Ascidine A (3,7-dihydro-1,8-dihydroxy-4-(4′-hydroxyphenyl)isoquinoline-3,7-dione (1), ascidine B (3,7-dihydro-1,8-dihydroxy-4-(4′-hydroxy-3′-iodophenyl)isoquinoline-3,7-dione (2), and ascidine C (3,7-dihydro-1,8-dihydroxy-4-(4′-hydroxy-3′,5′-diiodophenyl)isoquinoline-3,7-dione (3) represent a novel type of tyrosine-derived alkaloids.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-2017-0012/pdf

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