Interleukin-32 in Infection, Inflammation and Cancer Biology

Author:

Pavlovic Mladen1,Jovanovic Ivan2,Arsenijevic Nebojsa2

Affiliation:

1. Department of Surgery, Faculty of Medical Sciences , University of Kragujevac , Serbia

2. Center for Molecular Medicine and Stem Cell Research , Faculty of Medical Sciences , University of Kragujevac , Serbia

Abstract

Abstract Cytokines are small pleiotropic polypeptids secreted dominantly by the cells of the immune system. These polypeptids are main mediators of innate and acquired immunity, responsible for clonal expansion and differentiation of immune cells, initiation of immune response and enhancing of effector functions of leukocytes. Cytokine-related effects are most studied in the fields of inflammation, immunology, and cancer biology. In this review we discuss one of the most intriguing, recently discovered proinflammatory cytokine, interleukin 32.

Publisher

Centre for Evaluation in Education and Science (CEON/CEES)

Subject

General Medicine

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