Properties of an Adenosine Cyclic Phosphates Degrading Enzyme in Nicotiana tabacum L. var. Xanthi

Abstract

Abstract This work describes an enzyme which degrades adenosine 3′:5′-cyclic phosphate (3′ :5′-cyclic-AMP) and adenosine 2′:3′-cyclic phosphate (2′:3′-cyclic-AMP). The reaction pro­ ducts are 3′-AMP and 5′-AMP in case of 3′:5′-cyclic-AMP, 2′-AMP and 3′-AMP when 2′:3′-cyclic-AMP is given as substrate. Inorganic phosphate acts as a strong inhibitor, whereas theophyllin does not act up to a concentration of 10-3 m . Probably the adenosine cyclic phosphates degrading enzyme has no function in a ‘second messenger’ system with 3′:5′-cyclic-AMP.