Correlation between Diagnostic 59Fe2+-Absorption and Serum Ferritin Concentration in Man

Author:

Heinrich H. C.1,Brüggemann J.1,Gabbe E. E.1,Gläser M.1,Icagic Fatima,Pape Ellen

Affiliation:

1. Division of Medical Biochemistry, Institute of Physiological Chemistry, University Hospital Eppendorf, University of Hamburg

Abstract

Abstract A high correlation coefficient r = -0.832 (Pr≠0 <0.0001) was estimated in man for the inverse relationship between the diagnostic 59Fe2+-absorption and the serum ferritin concentration which is very close to the correlation r = - 0.88 as described for the relationship between the diagnostic 59Fe2+-absorption and the diffuse cytoplasmic storage iron in the bone marrow macrophages. The increase of the diagnostic 59Fe2+-absorption seems to be an earlier and more sensitive indicator of depleted iron stores whereas the serum ferritin decreases somewhat later during the development of iron deficiency.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

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