Factors of poor prognosis in newborns with a prenatal diagnosis of gastroschisis in Bogota, Colombia-Reference-Cited by-同舟云学术

Factors of poor prognosis in newborns with a prenatal diagnosis of gastroschisis in Bogota, Colombia

Published:2024-05-20 Issue:6 Volume:52 Page:665-670
ISSN:0300-5577
Container-title:Journal of Perinatal Medicine
language:en
Short-container-title:

Author:

Dávila Romero Viviana¹^ORCID,Aragón Mendoza Rafael L.²^ORCID,Molina-Giraldo Saulo³⁴,Herrera Emiliano M.⁵,Leal Elman H.²,Gallo Roa Roberto²,Rodríguez Ortiz Jorge A.⁶,Toro Angelica M.⁷^ORCID,Peña Rafael R.⁸,Gómez Hoyos Diana⁹,Nudelman Tammy⁹,Vargas Fiallo Cristian L.¹⁰

Affiliation:

1. Obstetrics and Gynecology Department , 27989 Universidad de La Sabana, Hospital Universitario de La Samaritana , Bogotá , Colombia

2. Obstetrics and Gynecology Department , 150244 GINECOHUS Research Group, Hospital Universitario de la Samaritana , Bogotá , Colombia

3. Sección de Terapia Fetal y Unidad de Cirugía Fetal, División de Medicina Materno Fetal, Obstetrics and Gynecology Department , Clínica Colsubsidio 94, Red de Investigación en Terapia y Cirugía Fetal – FetoNetwork Colombia , Bogotá , Colombia

4. Unidad de Medicina Materno Fetal, Departamento Ginecología y Obstetricia Facultad de Medicina , Universidad Nacional De Colombia , Bogotá , Colombia

5. Clínica Universitaria Colombia and Clínica Pediátrica Colsanitas , Bogotá , Colombia

6. Obstetrics and Gynecology Department , Hospital Simón Bolívar , Bogotá , Colombia

7. Obstetrics and Gynecology Department , 173049 Hospital Universitario San Ignacio , Bogotá , Colombia

8. Pediatric Surgery Department , 221984 Hospital Universitario Clínica San Rafael , Bogota , Colombia

9. Neonatology Department , 221984 Hospital Universitario Clínica San Rafael , Bogota , Colombia

10. Neonatology Department , Clínica Palermo , Bogota , Colombia

Abstract

Abstract Objectives To identify factors associated with poor prognoses in newborns with a prenatal diagnosis of gastroschisis in eight hospitals in Bogota, Colombia, from 2011 to 2022. Methods A multi-center retrospective case-control study was conducted on newborns with gastroschisis in eight hospitals in Bogota, Colombia. Poor prognosis was defined as the presence of sepsis, intestinal complications, or death. Results The study included 101 patients. Preterm newborns under 32 weeks had a poor neonatal prognosis (OR 6.78 95 % CI 0.75–319). Oligohydramnios (OR 4.95 95 % CI 1.15–21.32) and staged closure with silo (OR 3.48; 95 % CI 1.10–10.96) were risk factors for neonatal death, and intra-abdominal bowel dilation of 20–25 mm was a factor for the development of intestinal complications (OR 3.22 95 % CI 1.26–8.23). Conclusions Intra-abdominal bowel dilation between 20 and 25 mm was associated with intestinal complications, while oligohydramnios was associated with the risk of perinatal death, requiring increased antenatal surveillance of fetal wellbeing. Management with primary reduction when technically feasible is recommended in these infants, considering that the use of silos was associated with higher mortality.

Publisher

Walter de Gruyter GmbH

Link

https://www.degruyter.com/document/doi/10.1515/jpm-2023-0520/pdf

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