Affiliation:
1. Department of Hematology, The Affiliated Hospital of Qingdao University , No. 1677 of Wutaishan Road, Huangdao District , Qingdao 266000, Shandong , China
Abstract
Abstract
Waldenström macroglobulinemia (WM) rarely leads to pulmonary embolism. Due to its low incidence, the underlying pathophysiology, prognosis, and optimal treatment remain largely unexplored and uninvestigated. In this study, a patient with a double-clonal WM, a rare subtype, presented with pulmonary embolism. The patient had a small number of plasma cells without morphological abnormalities, and an effective therapeutic response was observed. Nonetheless, the clinical prognosis requires a long-term follow-up.
Subject
General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Neuroscience
Reference11 articles.
1. Morton LM, Turner JJ, Cerhan JR, Linet MS, Treseler PA, Clarke CA, et al. Proposed classification of lymphoid neoplasms for epidemiologic research from the Pathology Working Group of the International Lymphoma Epidemiology Consortium (InterLymph). Blood. 15 July 2007;110:695–708.
2. Braggio E, Philipsborn C, Novak A, Hodge L, Ansell S, Fonseca R. Molecular pathogenesis of Waldenstrom's macroglobulinemia. Haematologica. 2012;97(9):1281–90.
3. Chen DJ, Zhang XF, Wang MT, Yuan P, Yang M, Yuan Z. Lymphoplasmacytic lymphoma/Fahrenheit macroglobulinemia: A case report and literature review. Qinghai Med J. 2021;28(1):4.
4. Gertz MA. Waldenstrom macroglobulinemia: 2019 update on diagnosis, risk stratification, and management. Am J Hematol. 2019;94(2):266–76.
5. Innocenti S, Bacchi B, Allinovi M, Perfetto P, Antonioli E, Marchionni N, et al. A multidisciplinary case report of multiple myeloma with renal and cardiac involvement: a look beyond amyloidosis. BMC Nephrol. 2022;23(1):370.