Signalling pathways in the osteogenic differentiation of periodontal ligament stem cells-Reference-Cited by-同舟云学术

Signalling pathways in the osteogenic differentiation of periodontal ligament stem cells

Published:2023-01-01 Issue:1 Volume:18 Page:
ISSN:2391-5412
Container-title:Open Life Sciences
language:en
Short-container-title:

Author:

Ru Liuyu¹,Pan Bowen²,Zheng Jiwei¹³

Affiliation:

1. School of Stomatology, Xuzhou Medical University , Xuzhou , Jiangsu, 221000 , China

2. School of Medical Technology, Xuzhou Medical University , Xuzhou , Jiangsu, 221000 , China

3. Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Xuzhou Medical University , Xuzhou , Jiangsu, 221000 , China

Abstract

Abstract Periodontal ligament stem cells (PDLSCs) have multidirectional differentiation potential and self-renewal abilities and are important seed cells for the regenerative repair of periodontal tissues. In recent years, many studies have identified multiple signalling pathways involved in regulating the osteogenic differentiation of PDLSCs in an inflammatory environment. In this article, we review the osteogenic differentiation of PDLSCs in an inflammatory environment in terms of signalling pathways and provide new ideas for the regenerative treatment of periodontal tissues.

Publisher

Walter de Gruyter GmbH

Subject

General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Link

https://www.degruyter.com/document/doi/10.1515/biol-2022-0706/pdf

Reference54 articles.

1. Kwon T, Lamster IB, Levin L. Current concepts in the management of periodontitis. Int Dent J. 2021;71(6):462–76.

2. Yan B, Zhang H, Dai T, Gu Y, Qiu X, Hu C, et al. Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs. PLoS One. 2018;13(11):e0207760.

3. Gong W, Wang F, He Y, Zeng X, Zhang D, Chen Q. Mesenchymal stem cell therapy for oral inflammatory diseases: research progress and future perspectives. Curr Stem Cell Res Ther. 2021;16(2):165–74.

4. Wu B, An Y. New advances in the study of periodontal membrane stem cells in periodontal tissue regeneration. Oral Biomed. 2020;11(4):270–6.

5. Xu X, Zhang M, Xu F, Jiang S. Wnt signaling in breast cancer: Biological mechanisms, challenges and opportunities. Mol Cancer. 2020;19(1):165.

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