Model-based analysis and optimization of pressure-controlled ventilation of COPD patients in relation to BMI-Reference-Cited by-同舟云学术

Model-based analysis and optimization of pressure-controlled ventilation of COPD patients in relation to BMI

Published:2022-11-01 Issue:11 Volume:70 Page:957-967
ISSN:0178-2312
Container-title:at - Automatisierungstechnik
language:en
Short-container-title:

Author:

Hennigs Carlotta¹,Brehmer Kai¹,Hardel Tim Tristan²,Rostalski Philipp¹

Affiliation:

1. Institute for Electrical Engineering in Medicine, Universtät zu Lübeck , Luebeck , Germany

2. Zentrum für Anästhesiologie und Intensivmedizin, Klinik für Intensivmedizin, Universitätsklinikum Hamburg-Eppendorf , Hamburg , Germany

Abstract

Abstract This article presents an approach for model-based and personalized determination of inspiratory pressure and inspiratory time in pressure-controlled ventilation. Lung mechanics are strongly dependent on weight and affected by lung diseases such as COPD. Based on a simplified model of the lung with weight- and COPD-specific parameter selection and consideration of ventilation guidelines, the appropriate inspiratory pressure values are calculated. The results illustrate the effect of BMI on the computed optimal pressure-volume ratio. The findings provide a first step towards individualized decision support systems taking into account additional effects like BMI and specific lung diseases.

Publisher

Walter de Gruyter GmbH

Subject

Electrical and Electronic Engineering,Computer Science Applications,Control and Systems Engineering

Link

https://www.degruyter.com/document/doi/10.1515/auto-2022-0011/pdf

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