A fully automated touch-response behavior inspection pipeline on zebrafish larvae-Reference-Cited by-同舟云学术

A fully automated touch-response behavior inspection pipeline on zebrafish larvae

Published:2023-10-01 Issue:10 Volume:71 Page:845-852
ISSN:0178-2312
Container-title:at - Automatisierungstechnik
language:en
Short-container-title:

Author:

Wang Yanke¹,Pylatiuk Christian¹,Mikut Ralf¹,Peravali Ravindra²,Reischl Markus¹

Affiliation:

1. Institute for Automation and Applied Informatics, Karlsruhe Institute of Technology , Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen , Germany

2. Institute for Biological and Chemical Systems, Karlsruhe Institute of Technology , Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen , Germany

Abstract

Abstract A touch-evoked response of zebrafish larvae provides information on the mechanism of the gene functional expressions. Recently, an automated system has been developed for precise and repeated touch-response experimentation with minor human intervention. To quantify the collected data, we propose a fully automated multi-larvae touch-response behavior inspection pipeline based on larva tracking and segmentation. Experimental data with different treatments is analyzed by using the proposed inspection platform for demonstration, and the result proves that this platform can generate comparable touch-response behavior inspection readouts efficiently and automatically. The initial results were published in 31. Workshop Computational Intelligence, and this paper summarizes and extends the main work of the respective article.

Publisher

Walter de Gruyter GmbH

Subject

Electrical and Electronic Engineering,Computer Science Applications,Control and Systems Engineering

Link

https://www.degruyter.com/document/doi/10.1515/auto-2023-0013/pdf

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