Characterisation of newly emerged isolates of classical swine fever virus in China, 2014

Characterisation of newly emerged isolates of classical swine fever virus in China, 2014–2015

Published:2017-03-01 Issue:1 Volume:61 Page:1-9
ISSN:2450-8608
Container-title:Journal of Veterinary Research
language:en
Short-container-title:

Author:

Leng Chaoliang¹,Zhang Hongliang²,Kan Yunchao¹,Yao Lunguang¹,Li Mingliang¹,Zhai Hongyue¹,Li Zhen²,Liu Chunxiao²,Shi Hongfei¹,Ji Jun¹,Qiu Reng¹,Tian Zhijun²

Affiliation:

1. Henan Key Laboratory of Insect Biology in Funiu Mountain, Henan Provincial Engineering Laboratory of Insects Bio-reactor, China-UK-NYNU-RRes Joint Laboratory of Insect Biology, Nanyang Normal University, Nanyang 473061, China

2. State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China

Abstract

Abstract Introduction: In 2014–2015, the epidemic of classical swine fever (CSF) occurred in many large-scale pig farms in different provinces of China, and a subgenotype 2.1d of CSF virus (CSFV) was newly identified. Material and Methods: The phylogenetic relationship, genetic diversity, and epidemic status of the 2014–2015 CSFV isolates, 18 new CSFV isolates collected in 2015, and 43 other strains isolated in 2014–2015 were fully analysed, together with 163 CSFV reference isolates. Results: Fifty-two 2014–2015 isolates belonged to subgenotype 2.1d and nine other isolates belonged to subgenotype 2.1b. The two subgenotype isolates showed unique molecular characteristics. Furthermore, the 2.1d isolates were found to possibly diverge from 2.1b isolates. Conclusion: This study suggests that the Chinese CSFVs will remain pandemic.

Publisher

Walter de Gruyter GmbH

Subject

General Veterinary

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