Crystal structure of N-(acridin-9-yl)-2-(4-methylpiperidin-1-yl) acetamide monohydrate, C21H25N3O2-Reference-Cited by-同舟云学术

Crystal structure of N-(acridin-9-yl)-2-(4-methylpiperidin-1-yl) acetamide monohydrate, C₂₁H₂₅N₃O₂

Published:2024-04-05 Issue:3 Volume:239 Page:469-471
ISSN:1433-7266
Container-title:Zeitschrift für Kristallographie - New Crystal Structures
language:en
Short-container-title:

Author:

Jing Chen Yang¹^ORCID,Zhou Dan¹,Kan Yu Qian¹,Zhao Pei Rong¹²,Li Wen¹²

Affiliation:

1. School of Pharmaceutical Sciences , Zhengzhou University , Zhengzhou 450001 , People’s Republic of China

2. Henan Province Collaborative Innovation Center of New Drug Research and Safety Evaluation, Ministry of Education , Key Laboratory of Advanced Drug Preparation Technologies and Key Laboratory of Henan Province for Drug Quality and Evaluation , Zhengzhou 450001 , People’s Republic of China

Abstract

Abstract C21H25N3O2, triclinic, P1̄ (no. 2), a = 7.6536(6) Å, b = 11.027(1) Å, c = 12.6899(11) Å, α = 66.863(2)°, β = 80.598(2)°, γ = 71.772(2)°, V = 934.38(14) Å3, Z = 2, R gt(F) = 0.0679, wR ref(F 2) = 0.1150, T = 296 K.

Funder

Key Technologies R & D Program of Henan Province of China

Publisher

Walter de Gruyter GmbH

Link

https://www.degruyter.com/document/doi/10.1515/ncrs-2024-0050/pdf

Reference17 articles.

1. Sheldrick, G. M. SHELXTL – integrated space-group and crystal-structure determination. Acta Crystallogr. 2015, A71, 3–8.

2. Sheldrick, G. M. Crystal structure refinement with SHELXL. Acta Crystallogr. 2015, C71, 3–8; https://doi.org/10.1107/s2053229614024218.

3. Wainwright, M. Acridine-a neglected antibacterial chromophore. J. Antimicrob. Chemother. 2001, 47, 1–13; https://doi.org/10.1093/jac/47.1.1.

4. Chen, C. C., Zhang, Y. Q., Zhong, D. X., Huang, X.-H., Zhang, Y.-H., Jiang, W.-H., Li, M., Chen, Q., Wong, W.-L., Lu, Y.-J. The study of 9,10-dihydroacridine derivatives as a new and effective molecular scaffold for antibacterial agent development. Biochem. Biophys. Res. Commun. 2021, 546, 40–45; https://doi.org/10.1016/j.bbrc.2021.01.096.

5. Dai, X. J., Liu, Y., Wang, N., Chen, H. X., Wu, J. W., Xiong, X. P., Ji, S. K., Zhou, Y., Shen, L., Wang, S. P., Liu, H. M., Zheng, Y. C. Novel acridine-based LSD1 inhibitors enhance immune response in gastric cancer. Eur. J. Med. Chem. 2023, 259, 115684; https://doi.org/10.1016/j.ejmech.2023.115684.

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