Further Halotyrosine Derivatives from the Marine Sponge Suberea aff. praetensa-Reference-Cited by-同舟云学术

Further Halotyrosine Derivatives from the Marine Sponge Suberea aff. praetensa

Published:2002-08-01 Issue:7-8 Volume:57 Page:732-738
ISSN:1865-7125
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Kijjoa Anake¹²,Watanadilok Rawiwan³,Sonchaeng Pichai³,Sawangwong Pichan⁴,Pedro Madalena²,Nascimento Maria São José²,Silva Artur M. S.⁵,Eaton Graham⁶,Herz Werner⁷

Affiliation:

1. Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, 4099-003 Porto, Portugal

2. Centro de Estudos de Química Orgânica, Fitoquímica e Farmacologia de Universidade do Porto, Rua Anibal Cunha, 4050-017 Porto Portugal

3. Bangsaen Institute of Marine Science (BIMS), Burapha University, Bangsaen, Chonburi 20131, Thailand

4. Department of Aquatic Science, Faculty of Sciences, Burapha University, Bangsaen, Chonburi 20131, Thailand

5. Departamento de Química, Universidade de Aveiro, 3810 Aveiro, Portugal

6. Department of Chemistry, University of Leicester, University Road, Leicester LE 7RH, UK

7. Department of Chemistry and Biochemistry, The Florida State University, Tallahassee, FL 32306-4390, USA

Abstract

Reexamination of the marine sponge Suberea aff. praetensa, (Row) from the Gulf of Thailand furnished in addition to bromotyrosine derivatives found previously 5-bromo- and 5- chlorocavernicolin, cavernicolins 1 and 2, two other brominated tyrosine metabolites, a known bisoxazolidone and a new unusual rearranged tyrosine metabolite subereatensin. Several of the metabolites exhibited significant inhibitory effects against five human cancer cell lines.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-2002-7-831/pdf

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