Virucidal effects of mouthwashes or mouth rinses: a world of caution for molecular detection of SARS-CoV-2 in saliva

Author:

Lippi Giuseppe1ORCID,Nocini Riccardo2,Henry Brandon M.34,Plebani Mario5ORCID

Affiliation:

1. Section of Clinical Biochemistry and School of Medicine , University of Verona , Verona , Italy

2. Department of Surgery, Dentistry, Paediatrics and Gynaecology-Unit of Otorhinolaryngology , University of Verona , Verona , Italy

3. Clinical Laboratory, Division of Nephrology and Hypertension , Cincinnati Children’s Hospital Medical Center , Cincinnati , OH , USA

4. Disease Intervention & Prevention and Population Health Programs , Texas Biomedical Research Institute , San Antonio , TX , USA

5. Department of Medicine-DIMED , University of Padova , Padova , Italy

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry (medical),Clinical Biochemistry,Public Health, Environmental and Occupational Health,Health Policy,Medicine (miscellaneous)

Reference16 articles.

1. Ibrahimi, N, Delaunay-Moisan, A, Hill, C, Le Teuff, G, Rupprecht, JF, Thuret, JY, et al.. Screening for SARS-CoV-2 by RT-PCR: saliva or nasopharyngeal swab? Rapid review and meta-analysis. PLoS One 2021;16:e0253007. https://doi.org/10.1371/journal.pone.0253007.

2. Atieh, MA, Guirguis, M, Alsabeeha, NHM, Cannon, RD. The diagnostic accuracy of saliva testing for SARS-CoV-2: a systematic review and meta-analysis. Oral Dis 2021 Jun 3. https://doi.org/10.1111/odi.13934 [Epub ahead of print].

3. Fakhruddin, KS, Haiat, A, Ngo, HC, Panduwawala, C, Chang, JWW, Samaranayake, LP. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) viral positivity and their burden in saliva of asymptomatic carriers - a systematic review and meta-analysis. Acta Odontol Scand 2021;80:182–90.

4. Centers for Disease Control and Prevention. Interim guidelines for collecting and handling of clinical specimens for COVID-19 testing. Available from: https://www.cdc.gov/coronavirus/2019-ncov/lab/guidelines-clinical-specimens.html [Accessed 12 Jan 2022].

5. European Centre for Disease Control and Prevention. Considerations for the use of saliva as sample material for COVID-19 testing. Available from: https://www.ecdc.europa.eu/en/publications-data/considerations-use-saliva-sample-material-covid-19-testing [Accessed 12 Jan 2022].

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