In vivo/in vitro Studies of the Effects of the Type II Arabinogalactan Isolated from Maytenus ilicifolia Mart. ex Reissek on the Gastrointestinal Tract of Rats-Reference-Cited by-同舟云学术

In vivo/in vitro Studies of the Effects of the Type II Arabinogalactan Isolated from Maytenus ilicifolia Mart. ex Reissek on the Gastrointestinal Tract of Rats

Published:2012-08-01 Issue:7-8 Volume:67 Page:405-410
ISSN:1865-7125
Container-title:Zeitschrift für Naturforschung C
language:en
Short-container-title:

Author:

Baggio Cristiane H.¹,Freitas Cristina S.¹,Twardowschy André¹,Santos Ana Cristina dos¹,Mayer Bárbara¹,Potrich Francine B.¹,Cipriani Thales R.²,Sassaki Guilherme L.²,Iacomini Marcello²,Marques Maria Consuelo A.¹,Mesia-Vela Sonia³

Affiliation:

1. Department of Pharmacology, Sector of Biological Sciences, Universidade Federal do Paraná, Curitiba, PR, Brazil

2. Department of Biochemistry and Molecular Biology, Sector of Biological Sciences, Universidade Federal do Paraná, Curitiba, PR, Brazil

3. Mesia-Vela Department of Pharmacology, Sector of Biological Sciences, Universidade Federal do Paraná, Curitiba, PR, Brazil

Abstract

Type II arabinogalactan (AG) is a polysaccharide found in Maytenus ilicifolia (Celastraceae), a plant reputed as gastroprotective. Oral and intraperitoneal administration of the AG protected rats from gastric ulcers induced by ethanol. No alteration of mechanisms related to acid gastric secretion and gastrointestinal motility were observed. In vitro, the AG showed a potent scavenging activity against the radical of DPPH (2,2-diphenyl-1-picrylhydrazyl) with an IC50 value of 9.3 μM. However, the mechanism of the gastroprotective action remains to be identified.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://www.degruyter.com/document/doi/10.1515/znc-2012-7-808/pdf

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phytochemistry and Pharmaceutical Technology Studies on Monteverdia ilicifolia (Maytenus ilicifolia): a Traditionally Used Medicinal Plant;Revista Brasileira de Farmacognosia;2022-10-03

2. Gastroprotective polysaccharide from natural sources: Review on structure, mechanism, and structure–activity relationship;Food Frontiers;2022-08-12

3. Gastroprotective activity of polysaccharide from the fruiting body of Hericium erinaceus against acetic acid-induced gastric ulcer in rats and structure of one bioactive fraction;International Journal of Biological Macromolecules;2022-06

4. Plants arabinogalactans: From structures to physico-chemical and biological properties;Biotechnology Advances;2021-12