Phytochemistry and neuroprotective effects of Eclipta alba (L.) Hassk

Author:

Guenné Samson1,Ouattara Nabèrè21,Ouédraogo Noufou1,Ciobica Alin345,Hilou Adama1,Kiendrebéogo Martin1

Affiliation:

1. Laboratory of Applied Biochemistry and Chemistry (LA.BIO.C.A), University Ouaga I Pr Joseph KI-ZERBO, 03 P.O. Box: 7021, Ouagadougou03, Burkina Faso

2. University of Dedougou, BP 176, Dedougou, Burkina Faso

3. Academy of Romanian Scientists, Splaiul Independentei nr. 54, sector 5, 050094BucurestiRomania

4. Center of Biomedical Research, Romanian Academy, Iasi, B dul Carol I, no 8 Romania

5. Department of Research, Faculty of Biology, Alexandru Ioan Cuza University, B dul Carol I, no 11, Iasi, Romania

Abstract

AbstractEclipta alba (L.) Hassk. or Eclipta prostrata (Linn.) or Eclipta erecta (Linn.) is an herbaceous plant well known in Asian as African traditional medicines. These extracts are used in traditional medicine for treatment of microbial diseases and certain metabolic disorders. This review aimed to investigate phytochemical profile and neuroprotective effects of E. alba (L.) Hassk. Several compounds belonging to the families of phenolics, alkaloids, terpenoids and polysaccharides have been isolated, identified or characterized from E. alba extracts. This plant has a diverse neuropharmacological profile. Thus, its extract improves cognitive deficits and also attenuated epileptic seizures. Phytomolecules implicated in these potentials are Eclalbasaponin II and luteolin, respectively. This document updates isolated and identified organic compounds from the extracts of E. alba and reviews their neuropharmacological activities.

Publisher

Walter de Gruyter GmbH

Subject

Complementary and alternative medicine

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