Verhalten von Viren gegenüber dem Bayer-Präparat A 139

Abstract

Bayer A 139, an ethylene-iminoquinone, reacts with nucleic acids at pH ≦ 7, leaving the protein intact. This compound inactivates fowl plaque virus, NDV, and TMV-RNA, following first order kinetics. In the case of fowl plaque virus it does not destroy the hemagglutinating, neuraminidase, interference, and antigenic activities. Intact TMV and ME-virus are not inactivated. With fowl plaque virus a phenomenon discussed as multiplicity reactivation was observed.