New Withanolides from Fresh Berries of Withania somnifera

Author:

Lal Payare1,Misra Laxminarain1,Sangwan Rajender S.1,Tuli Rakesh2

Affiliation:

1. Central Institute of Medicinal and Aromatic Plants, P.O.- CIMAP, Lucknow- 226015, India

2. National Botanical Research Institute, Lucknow- 226001, India

Abstract

Abstract The chloroform extract of the fresh berries of Withania somnifera has been investigated to afford stigmasterol, its glucoside, withanone, 27-hydroxy withanolide A along with two new withanolides, namely, iso-withanone (1) and 6α,7α-epoxy-1α,3β ,5α-trihydroxy-witha-24-enolide (2). Compound 1 possesses an uncommon 17α-oriented side chain whereas compound 2 has 1α,3β - dihydroxy group which is a molecule of biogenetic significance for withasteroids.

Publisher

Walter de Gruyter GmbH

Subject

General Chemistry

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