Periodontal, metabolic, and cardiovascular disease: Exploring the role of inflammation and mental health-Reference-Cited by-同舟云学术

Periodontal, metabolic, and cardiovascular disease: Exploring the role of inflammation and mental health

Published:2018-11-01 Issue:1 Volume:29 Page:124-163
ISSN:2195-4720
Container-title:Pteridines
language:en
Short-container-title:

Author:

Makkar Hina¹,Reynolds Mark A.²,Wadhawan Abhishek¹³,Dagdag Aline¹,Merchant Anwar T.⁴,Postolache Teodor T.¹⁵⁶

Affiliation:

1. Mood and Anxiety Program, Department of Psychiatry, University of Maryland School of Medicine, Baltimore , USA

2. Department of Advanced Oral Sciences & Therapeutics, University of Maryland School of Dentistry, Baltimore , USA

3. Saint Elizabeths Hospital, Psychiatry Residency Training Program, Washington , USA

4. Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia , USA

5. Rocky Mountain Mental Illness Research Education and Clinical Center (MIRECC), Veterans Integrated Service Network, Military and Veteran Microbiome Consortium for Research and Education (MVM-CoRE), Denver , USA

6. Mental Illness Research, Education and Clinical Center (MIRECC), Veterans Integrated Service Network, VA Capitol Health Care Network, Baltimore , USA

Abstract

Abstract Previous evidence connects periodontal disease, a modifiable condition affecting a majority of Americans, with metabolic and cardiovascular morbidity and mortality. This review focuses on the likely mediation of these associations by immune activation and their potential interactions with mental illness. Future longitudinal, and ideally interventional studies, should focus on reciprocal interactions and cascading effects, as well as points for effective preventative and therapeutic interventions across diagnostic domains to reduce morbidity, mortality and improve quality of life.

Publisher

Walter de Gruyter GmbH

Subject

Clinical Biochemistry,Molecular Medicine,Biochemistry

Link

https://www.degruyter.com/document/doi/10.1515/pteridines-2018-0013/pdf

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