Experimental Research Into the Effect of Hyperbaric Exposures-Reference-Cited by-同舟云学术

Experimental Research Into the Effect of Hyperbaric Exposures

Published:2017-12-20 Issue:4 Volume:61 Page:43-48
ISSN:2084-0535
Container-title:Polish Hyperbaric Research
language:en
Short-container-title:

Author:

Dolatkowski Augustyn¹,Doboszyński Tadeusz¹,Łokucijewski Bogdan¹

Affiliation:

1. Department of Maritime Medicine of the Military Medical Academy, Gdynia , Poland

Abstract

Abstract Numerous research works indicate that staying in a hyperbaric environment is a stressor. We have undertaken studies using an animal model to determine the effect of hyperbaria on adrenocortical secretion and the level of adrenal ascorbic acid (a.a.a.). The research was conducted on 70 male hooded rats, which were divided into groups and subjected to hyperbaric air and oxygen at an overpressure of 1 and 3 atn, with some of the animals being additionally burdened with physical effort (swimming). It was found that short-term exposures (30 minutes) of rats to hyperbaric conditions caused a decrease in the content of a.a.a. With a prolonged (3-hour) exposure to 3 atm air the a.a.a. content returns to a normal level. A reduction in the a.a.a. content indicates the presence of stress in hyperbaric conditions in the rat, however, it does not allow to determine its intensity with the method used in the study.

Publisher

Walter de Gruyter GmbH

Subject

General Medicine

Reference21 articles.

1. 1. Aschan G.: "Oxygen deficiency and oxygen poisoning as stress factors". Acta Soc.Med.Upsal.58, 265-268, 1953;

2. 2. Bagramian E.R.: "O wlijanii narkoza na reakciju gipofizo-nadpoczecznikowoj sistiemy na naprjażenijo", Farmakoł. Toksikoł., 27, 335-338, 1964.

3. 3. Bean J.W., Johnson P.C.: Am.J.Physiol., 179, 410-414, 1954;

4. 4. Bean J.W.: "Tris buffer, CO2 and sympatho-adrenal system in reactions to O2 at high pressure", Am.J.Physiol.,201, 737-739, 1961;

5. 5. Boulouard R.: "Effects of cold and starvation on adrenocartical activity of rats", Fed.Proc., 22, 750-754, 1963;