Author:
Elgina Svetlana,Artymuk Natalia,Nikulina Elena
Abstract
Abstract
Background
The objective was to estimate ovarian reserve in adolescent girls born prematurely.
Materials and methods
Two hundred adolescent girls aged 15–16 years who were born prematurely and full term were studied with laboratory, ultrasound and statistical methods.
Results
Statistically significant differences of the main parameters that characterize ovarian reserve in adolescent girls born prematurely compared to those born full term were specified. The levels of estradiol (p = 0.027), anti-Müllerian hormone (p = 0.0004) and inhibin В (p = 0.015) were lower in the girls born prematurely and follicle stimulating (p = 0.0001) and lutenizing (p = 0.002) hormone levels were higher. The ultrasound imaging (USI) findings of the uterus and appendages were also different. Adolescent girls born prematurely had longer uterus cervix, smaller sizes of endometrial echo, smaller ovarian sizes and fewer follicles in them.
Conclusions
Adolescent girls born prematurely have different parameters of ovarian reserve compared to those of girls born full term.
Subject
Endocrinology,Molecular Biology,General Medicine,Endocrinology, Diabetes and Metabolism
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