Author:
Best Damian,Bhattacharya Siladitya
Abstract
AbstractThe prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.
Subject
Endocrinology,Molecular Biology,General Medicine,Endocrinology, Diabetes and Metabolism
Reference90 articles.
1. Effect of Roux - en gastric bypass surgery on the sex steroids and quality of life in obese men;Hammoud;J Clin Endocrinol Metab,2009
2. Relationship of clomiphene dose and patient weight to successful treatment;Dickey;Hum Reprod,1997
3. National Collaborating Centre for Women s and Children Fertility assessment and treatment of people with fertility problems clinical guideline;NICE;Health,2013
4. Body mass index is inversely related to intrafollicular hCG concentrations embryo quality and outcome;Carrell;Reprod Biomed Online,2001
5. Impact of obesity on female fertility and fertility treatment Women;Zain;Health,2008
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