Amniotic fluid LPCAT1 mRNA correlates with the lamellar body count-Reference-Cited by-同舟云学术

Amniotic fluid LPCAT1 mRNA correlates with the lamellar body count

Published:2016-01-01 Issue:5 Volume:44 Page:
ISSN:1619-3997
Container-title:Journal of Perinatal Medicine
language:
Short-container-title:

Author:

Welch Robert A.,Shaw Michael K.,Welch Kathryn C.

Abstract

AbstractLysophosphatidylcholine acyltransferase 1 (LPCAT1) is required in the biosynthesis of pulmonary surfactant. This short communication describes our assessment of LPCAT1 mRNA levels in human amniotic fluid. We found a direct correlation between LPCAT1 mRNA copies and the amniotic fluid lamellar body count (LBC). This finding corroborates an association between LPCAT1 and surfactant phospholipid biosynthesis in humans. It may provide a model for future research in perinatal medicine.

Publisher

Walter de Gruyter GmbH

Subject

Obstetrics and Gynaecology,Pediatrics, Perinatology, and Child Health

Link

https://www.degruyter.com/document/doi/10.1515/jpm-2015-0008/pdf

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5. Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells;Proc Natl Acad Sci USA.,2008

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