1. Department of Chemistry in Pharmaceutical Sciences, School of Pharmacy , Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i +12 , Plaza Ramón y Cajal s/n , E-28040 Madrid , Spain
2. Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) , Madrid , Spain , Tel.: +34913941861, Fax: +34913941786