Selective nematocidal effects of essential oils from two cultivated Artemisia absinthium populations

Author:

García-Rodríguez Juan José,Andrés María-Fé1,Ibañez-Escribano Alexandra,Julio Luis F.1,Burillo Jesús2,Bolás-Fernández Francisco,González-Coloma Azucena1

Affiliation:

1. Instituto de Ciencias Agrarias, CSIC. Serrano 115-dpdo, 28006 Madrid, Spain

2. CITA-Gobierno de Aragón, Avda. Montañana 930, 50059 Zaragoza, Spain

Abstract

Abstract Essential oils (EOs) obtained from two crops and populations of thujone-free cultivated Artemisia absinthium were tested against two nematode models, the mammalian parasite Trichinella spiralis, and the plant parasitic root knot nematode Meloidogyne javanica. The EOs were characterized by the presence of (Z)-epoxyocimene and chrysanthenol as major components and showed time and population dependent quantitative and qualitative variations in composition. The EOs showed a strong ex vivo activity against the L1 larvae of the nematode Trichinella spiralis with a reduction of infectivity between 72 and 100% at a dose range of 0.5–1 mg/ml in absence of cytotoxicity against mammalian cells. Moreover, the in vivo activity of the EO against T. spiralis showed a 66% reduction of intestinal adults. However, these oils were not effective against M. javanica.

Publisher

Walter de Gruyter GmbH

Subject

General Biochemistry, Genetics and Molecular Biology

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