Bis-heterocycles. Part I: tetrahydro-5,5′- bi(1,2,4-triazin-6-ones)
Author:
Mohammad Hanan H.1, El-Abadelah Mustafa M.1, Sabri Salim S.1, Awwadi Firas F.1, Voelter Wolfgang2
Affiliation:
1. Chemistry Department, Faculty of Science , The University of Jordan , Amman 11942 , Jordan 2. Interfakultäres Institut für Biochemie, Universität Tübingen , Hoppe-Seyler Straße 4 , 72076 Tübingen , Germany
Abstract
Abstract
Selected sets of tetrahydro-5,5′-bi(1,2,4-triazines) (1–3) appended with acetyl, benzoyl, and ester moieties at C-3 position and N-1 (p-substituted)phenyl ring have been prepared and characterized by spectral (IR, NMR, MS) data and X-ray diffraction for compound 3a. Their synthesis was achieved in high yield via the reaction of diethyl aminomalonate with various N-(aryl)hydrazonoyl chlorides in the presence of triethylamine.
Publisher
Walter de Gruyter GmbH
Subject
General Chemistry
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